AHR is a master regulator of diverse pathways in endogenous metabolism

Complex heatmaps reveal patterns and correlations in multidimensional genomic data

Zuguang Gu, Roland Eils, Matthias Schlesner · Bioinformatics · 2016 · 10.2K citations · Full text

Quantitative prediction of cellular metabolism with constraint-based models: the COBRA Toolbox v2.0

Jan Schellenberger, Richard Que, Ronan M. T. Fleming et al. · Nature Protocols · 2011 · 1.9K citations · Full text

Metabolic Network, Systems Biology, Engineering +13

COBRApy: COnstraints-Based Reconstruction and Analysis for Python

Ali Ebrahim, Joshua A. Lerman, Bernhard Ø. Palsson et al. · BMC Systems Biology · 2013 · 1.4K citations · Full text

A gut bacterial pathway metabolizes aromatic amino acids into nine circulating metabolites

Dylan Dodd, Matthew H. Spitzer, William Van Treuren et al. · Nature · 2017 · 1.3K citations · Full text

Dysbiosis, Biochemistry, Medicine +12

Symbiotic Bacterial Metabolites Regulate Gastrointestinal Barrier Function via the Xenobiotic Sensor PXR and Toll-like Receptor 4

Madhukumar Venkatesh, Subhajit Mukherjee, Hongwei Wang et al. · Immunity · 2014 · 955 citations · Full text

Xenobiotic Sensor Pxr, Dysbiosis, Mucosal Immunology +11