Adipocyte IRE1α promotes PGC1α mRNA decay and restrains adaptive thermogenesis

Mutation of the mouse klotho gene leads to a syndrome resembling ageing.

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XBP1 mRNA Is Induced by ATF6 and Spliced by IRE1 in Response to ER Stress to Produce a Highly Active Transcription Factor

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Transcriptional Regulation, Signal Transduction, Molecular Regulation +9

A Cold-Inducible Coactivator of Nuclear Receptors Linked to Adaptive Thermogenesis

Pere Puigserver, Zhidan Wu, Cheol Won Park et al. · Cell · 1998 · 3.8K citations · Full text

Signal Transduction, Receptor (Biochemistry), Molecular Biology +4

A global double‐fluorescent Cre reporter mouse

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Beige Adipocytes Are a Distinct Type of Thermogenic Fat Cell in Mouse and Human

Jun Wu, Pontus Boström, Lauren M. Sparks et al. · Cell · 2012 · 3.3K citations · Full text

Obesity, Body Composition, Thermogenic Fat Cell +12