Regulatory B cells in patients suffering from inborn errors of immunity with severe immune dysregulation

Disparate CD4+ lamina propria (LP) lymphokine secretion profiles in inflammatory bowel disease. Crohn’s disease LP cells manifest increased secretion of IFN-γ, whereas ulcerative colitis LP cells manifest increased secretion of IL-5

Ivan J. Fuss, Markus F. Neurath, Monica Boirivant et al. · The Journal of Immunology · 1996 · 1.2K citations · Full text

Life Sciences, Immunology, Pathology +17

Characterization of a rare IL-10–competent B-cell subset in humans that parallels mouse regulatory B10 cells

Yohei Iwata, Takashi Matsushita, Mayuka Horikawa et al. · Blood · 2010 · 1.1K citations · Full text

Life Sciences, Cell Biology, Immunology +12

Human Inborn Errors of Immunity: 2019 Update of the IUIS Phenotypical Classification

Aziz Bousfiha, Leïla Jeddane, Capucine Pïcard et al. · Journal of Clinical Immunology · 2020 · 691 citations · Full text

Life Sciences, Genetics, Immunology +12

Patients with LRBA deficiency show CTLA4 loss and immune dysregulation responsive to abatacept therapy

Bernice Lo, Kejian Zhang, Wei Lü et al. · Science · 2015 · 684 citations

Life Sciences, Immunology, Pharmacology +17

Deleterious Mutations in LRBA Are Associated with a Syndrome of Immune Deficiency and Autoimmunity

Gabriela López‐Herrera, Giacomo Tampella, Qiang Pan‐Hammarström et al. · The American Journal of Human Genetics · 2012 · 525 citations · Full text

Life Sciences, Genetics, Immunology +15