Concepedia

Integrated Machine Learning and Single-Sample Gene Set Enrichment Analysis Identifies a TGF-Beta Signaling Pathway Derived Score in Headneck Squamous Cell Carcinoma

Sheng Wu, Xiangkang Lv, Yilin Li, Xinyi Gao, Zhiqi Ma, Xiao Fu, Yong Li

Journal of Oncology · 2022 · 44 citations · 24 references

DOIFull text

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Abstract

We first construct and validate TGF-<i>β</i> characteristics that can predict immune microenvironment phenotypes and immunotherapeutic effect in multiple datasets. Noteworthy, TGF-<i>β</i> risk score is helpful for individualized precise treatment of patients with the head and neck squamous cell carcinoma.

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The Society for Immunotherapy of Cancer consensus statement on immunotherapy for the treatment of squamous cell carcinoma of the head and neck (HNSCC)

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Association of Oral Microbiome With Risk for Incident Head and Neck Squamous Cell Cancer

Richard B. Hayes, Jiyoung Ahn, Xiaozhou Fan et al. · JAMA Oncology · 2018 · 316 citations · Full text