Concepedia

Synthesis and screening of novel 4-N-heterocyclic-2-aryl-6,7,8-trimethoxyquinazolines as antiproliferative and tubulin polymerization inhibitors

Ashish Ranjan Dwivedi, Suraj Singh Rawat, Vijay Kumar, Naveen Kumar, Piyush Anand, Ravi Prakash Yadav, Somesh Baranwal, Amit Prasad, Vinod Kumar

Bioorganic & Medicinal Chemistry · 2022 · 15 citations · 38 references

DOI

Concepts

References

38

Molecular dynamics---Scalable algorithms for molecular dynamics simulations on commodity clusters

K. J. Bowers, Federico D. Sacerdoti, John K. Salmon et al. · 2006 · 2.5K citations

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Analysis of the Mitochondrial Membrane Potential Using the Cationic JC-1 Dye as a Sensitive Fluorescent Probe

Farzane Sivandzade, Aditya Bhalerao, Luca Cucullo · BIO-PROTOCOL · 2019 · 862 citations · Full text

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Potent, Orally Active Heterocycle-Based Combretastatin A-4 Analogues:  Synthesis, Structure−Activity Relationship, Pharmacokinetics, and In Vivo Antitumor Activity Evaluation

Le Wang, Keith W. Woods, Qun Li et al. · Journal of Medicinal Chemistry · 2002 · 421 citations · Full text

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The Novel Microtubule-Destabilizing Drug BAL27862 Binds to the Colchicine Site of Tubulin with Distinct Effects on Microtubule Organization

A.E. Prota, Franck Danel, Felix Bachmann et al. · Journal of Molecular Biology · 2014 · 307 citations

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Variations in the colchicine-binding domain provide insight into the structural switch of tubulin

Audrey Dorléans, Benoı̂t Gigant, Raimond B. G. Ravelli et al. · Proceedings of the National Academy of Sciences · 2009 · 268 citations · Full text

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