Concepedia

Chemical Pathways of Peptide Degradation. II. Kinetics of Deamidation of an Asparaginyl Residue in a Model Hexapeptide

Kamlesh C. Patel, Ronald T. Borchardt

Pharmaceutical Research · 1990 · 279 citations · 38 references

DOI

Concepts

References

38

Solid Phase Peptide Synthesis

John Morrow Stewart · Journal of Macromolecular Science Part A - Chemistry · 1976 · 1.8K citations

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Deamidation, isomerization, and racemization at asparaginyl and aspartyl residues in peptides. Succinimide-linked reactions that contribute to protein degradation.

Terrence L. Geiger, Steven Clarke · Journal of Biological Chemistry · 1987 · 1.3K citations · Full text

, , +16

Succinimide Formation from Aspartyl and Asparaginyl Peptides as a Model for the Spontaneous Degradation of Proteins

Robert C. Stephenson, Steven Clarke · Journal of Biological Chemistry · 1989 · 518 citations · Full text

, , +14

The Mechanism of Irreversible Enzyme Inactivation at 100°C

Tim J. Ahern, Alexander M. Klibanov · Science · 1985 · 446 citations

, , +17

[14] Cleavage at AsnGly bonds with hydroxylamine

Paul Börnstein, Gary Balian · Methods in enzymology on CD-ROM/Methods in enzymology · 1977 · 417 citations

, , +9