Gambogenic acid alleviates kidney fibrosis via epigenetic inhibition of EZH2 to regulate Smad7-dependent mechanism

Snail1-induced partial epithelial-to-mesenchymal transition drives renal fibrosis in mice and can be targeted to reverse established disease

María T. Grande, Berta Sanchez‐Laorden, Cristina López-Blau et al. · Nature Medicine · 2015 · 801 citations · Full text

Medicine, Cell Biology, Pathology +10

Transforming Growth Factor β-1 Induces Snail Transcription Factor in Epithelial Cell Lines

Héctor Peinado, Miguel Quintanilla, Amparo Cano · Journal of Biological Chemistry · 2003 · 637 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +16

The case for early identification and intervention of chronic kidney disease: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference

Michael G. Shlipak, Sri Lekha Tummalapalli, L. Ebony Boulware et al. · Kidney International · 2020 · 573 citations · Full text

Medicine, Health Policy, Nephrology +17

Role of Reactive Oxygen Species in TGF-β1-Induced Mitogen-Activated Protein Kinase Activation and Epithelial-Mesenchymal Transition in Renal Tubular Epithelial Cells

Dong Young Rhyu, Yanqiang Yang, Hunjoo Ha et al. · Journal of the American Society of Nephrology · 2005 · 521 citations

Life Sciences, Cell Biology, Nephrology +17

TGF-β in Renal Injury and Disease

Erwin P. Böttinger · Seminars in Nephrology · 2007 · 338 citations

Medicine, Nephrology, Pathology +12