Concepedia

Ptchd1 mediates opioid tolerance via cholesterol-dependent effects on μ-opioid receptor trafficking

Nycole A. Maza, Dandan Wang, Cody W. Kowalski, Hannah M. Stoveken, Maria Dao, Omar K. Sial, Andrew C. Giles, Brock Grill, Kirill A. Martemyanov

Nature Neuroscience · 2022 · 23 citations · 42 references

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42

An anatomically comprehensive atlas of the adult human brain transcriptome

Michael Hawrylycz, Ed S. Lein, Angela Guillozet-Bongaarts et al. · Nature · 2012 · 3.3K citations · Full text

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Loss of morphine-induced analgesia, reward effect and withdrawal symptoms in mice lacking the µ-opioid-receptor gene

Hans W. D. Matthes, Rafaël Maldonado, Frédéric Simonin et al. · Nature · 1996 · 1.7K citations

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PHARMACOLOGICAL EFFECTS PRODUCED BY INTRACEREBRAL INJECTION OF DRUGS IN THE CONSCIOUS MOUSE

Thomas J. Haley, WF McCormick · British Journal of Pharmacology and Chemotherapy · 1957 · 1.5K citations · Full text

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Crystal structure of the µ-opioid receptor bound to a morphinan antagonist

Aashish Manglik, Andrew C. Kruse, Tong Sun Kobilka et al. · Nature · 2012 · 1.4K citations

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μ-Opioid receptor desensitization by β-arrestin-2 determines morphine tolerance but not dependence

Laura Bohn, Raul R. Gainetdinov, Fang‐Tsyr Lin et al. · Nature · 2000 · 916 citations

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