Regulation of TFEB nuclear localization by HSP90AA1 promotes autophagy and longevity

Shaosong Yang, Tiejian Nie, Hua She, Kai Tao, Fangfang Lu, Yiman Hu, Lu Huang, Lin Zhu, Dayun Feng, Dan He,

Autophagy · 2022 · 66 citations · 43 references

DOIFull text

Open access

Concepts

Abstract

; CDK5: cyclin-dependent kinase 5; CDK5R1: cyclin dependent kinase 5 regulatory subunit 1; CR: calorie restriction; FUDR: 5-fluorodeoxyuridine; HSP90AA1: heat shock protein 90 alpha family class A member 1; MAP1LC3: microtubule associated protein 1 light chain 3; NB: novobiocin sodium; SQSTM1: sequestosome 1; TFEB: transcription factor EB; WT: wild type.

References

43