Essential control of mitochondrial morphology and function by chaperone-mediated autophagy through degradation of PARK7

Bao Wang, Zhibiao Cai, Kai Tao, +6

Autophagy

MitophagyMitochondrial DysfunctionCell DeathOxidative StressCell Autophagy +16

Chaperone‐mediated autophagy degrades Keap1 and promotes Nrf2‐mediated antioxidative response

Lin Zhu, Shulei He, Lu Huang, +7

Aging Cell

Reductive StressCell AutophagyMitophagyRedox SignalingBiochemistry +11

Resveratrol attenuates MPP+-induced mitochondrial dysfunction and cell apoptosis via AKT/GSK-3β pathway in SN4741 cells

Weijun Zeng, Wei Zhang, Fangfang Lu, +2

Neuroscience Letters

BiochemistryMitochondrial FunctionCell ApoptosisMpp+-induced Mitochondrial DysfunctionApoptosis +8

Several miRNAs derived from serum extracellular vesicles are potential biomarkers for early diagnosis and progression of Parkinson’s disease

Shulei He, Lu Huang, Ci Shao, +7

Translational Neurodegeneration

Regulation of ER stress-induced autophagy by GSK3β-TIP60-ULK1 pathway

Tiejian Nie, Shaosong Yang, Hongwei Ma, +8

Cell Death and Disease

Regulation of TFEB nuclear localization by HSP90AA1 promotes autophagy and longevity

Shaosong Yang, Tiejian Nie, Hua She, +12

Autophagy

Histone demethylase KDM2B upregulates histone methyltransferase EZH2 expression and contributes to the progression of ovarian cancer in vitro and in vivo

Yan Kuang, Fangfang Lu, Jianfeng Guo, +5

OncoTargets and Therapy

Salidroside Protects Against 6-Hydroxydopamine-Induced Cytotoxicity by Attenuating ER Stress

Kai Tao, Bao Wang, Dayun Feng, +6

Neuroscience Bulletin

Attenuating Er StressMedicineLipid PeroxidationPharmacotherapyPharmacology +1

Transcription factor myocyte enhancer factor 2D regulates interleukin-10 production in microglia to protect neuronal cells from inflammation-induced death

Shaosong Yang, Li Gao, Fangfang Lu, +6

Journal of Neuroinflammation

Cambogin Induces Caspase-Independent Apoptosis through the ROS/JNK Pathway and Epigenetic Regulation in Breast Cancer Cells

Kaikai Shen, Jianling Xie, Hua Wang, +5

Molecular Cancer Therapeutics

Breast OncologyChemoprevention StrategyApoptosisCell DeathOxidative Stress +16