Concepedia

Extracellular histones induce inflammation and senescence of vascular smooth muscle cells by activating the AMPK/FOXO4 signaling pathway

Hang Yang, Yong-Yan Luo, Lue-Tao Zhang, Kai-Ran He, Xiaojun Lin

Inflammation Research · 2022 · 18 citations · 32 references

DOI

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References

32

Extracellular histones are major mediators of death in sepsis

Jun Xu, Xiaomei Zhang, Rosana Pelayo et al. · Nature Medicine · 2009 · 1.5K citations · Full text

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Circulating Histones Are Mediators of Trauma-associated Lung Injury

Simon T. Abrams, Nan Zhang, Joanna Manson et al. · American Journal of Respiratory and Critical Care Medicine · 2012 · 588 citations · Full text

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Extracellular Histones Are Mediators of Death through TLR2 and TLR4 in Mouse Fatal Liver Injury

Jun Xu, Xiaomei Zhang, Marc Monestier et al. · The Journal of Immunology · 2011 · 521 citations · Full text

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The Epidemiology of Sepsis in Chinese ICUs: A National Cross-Sectional Survey

Jianfeng Xie, Hongliang Wang, Yan Kang et al. · Critical Care Medicine · 2019 · 493 citations

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Endogenous histones function as alarmins in sterile inflammatory liver injury through Toll-like receptor 9 in mice

Hai Huang, John Evankovich, Wei Yan et al. · Hepatology · 2011 · 350 citations · Full text

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