Mucin 1 Inhibits Ferroptosis and Sensitizes Vitamin E to Alleviate Sepsis‐Induced Acute Lung Injury through GSK3<i>β</i>/Keap1‐Nrf2‐GPX4 Pathway

Abstract

Our study was the first to explore the changes of iron metabolism indicators in ALI/ARDS of sepsis, clarify the important role of ferroptosis in ALI/ARDS induced by sepsis, and reveal the effects and specific mechanisms of MUC1 in regulating ferroptosis, as well as the sensitization on vitamin E.