ACSL4 is overexpressed in psoriasis and enhances inflammatory responses by activating ferroptosis

ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition

Sebastian Doll, Bettina Proneth, Yulia Y. Tyurina et al. · Nature Chemical Biology · 2016 · 4.1K citations · Full text

Life Sciences, Biochemistry, Cell Biology +14

Oxidized arachidonic and adrenic PEs navigate cells to ferroptosis

Valerian E. Kagan, Gaowei Mao, Feng Qu et al. · Nature Chemical Biology · 2016 · 2.8K citations · Full text

Life Sciences, Biochemistry, Cell Biology +7

PKCβII phosphorylates ACSL4 to amplify lipid peroxidation to induce ferroptosis

Hai‐Liang Zhang, Bingxin Hu, Zhi‐Ling Li et al. · Nature Cell Biology · 2022 · 547 citations

Life Sciences, Biochemistry, Cell Biology +11

The Global, Regional, and National Burden of Psoriasis: Results and Insights From the Global Burden of Disease 2019 Study

Giovanni Damiani, Nicola Luigi Bragazzi, C. Karimkhani Aksut et al. · Frontiers in Medicine · 2021 · 346 citations · Full text

Medicine, Dermatology, Health Policy +17

Inhibition of keratinocyte ferroptosis suppresses psoriatic inflammation

Yanhong Shou, Lu Yang, Yongsheng Yang et al. · Cell Death and Disease · 2021 · 225 citations · Full text

Medicine, Dermatology, Pathology +17