Effects of α5 <scp>GABA<sub>A</sub></scp> receptor modulation on social interaction, memory, and neuroinflammation in a mouse model of Alzheimer's disease - Concepedia

Concepedia

Publication | Open Access

Effects of α5 <scp>GABA<sub>A</sub></scp> receptor modulation on social interaction, memory, and neuroinflammation in a mouse model of Alzheimer's disease

DOI Full Paper Access

12

Citations

48

References

2022

Year

Jovana Aranđelović, Anja Santrač, Bojan Batinić, Lidija Todorović, Vladimir D. Stevanović, V. V. N. Phani Babu Tiruveedhula, Dishary Sharmin, Farjana Rashid, Boban Stanojević, James M. Cook,

CNS Neuroscience & Therapeutics

Abstract

PAM and NAM failed to exert favorable behavioral effects in transgenic animals. Suppression of neuroinflammation obtained with NAM calls for more studies with GABAergic ligands in amyloid beta- and/or tau-dependent models with prominent neuroinflammation.

References

	Year	Citations

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