A synthetic lethal strategy using PARP and ATM inhibition for overcoming trastuzumab resistance in HER2-positive cancers

Web-Based Survival Analysis Tool Tailored for Medical Research (KMplot): Development and Implementation

András Lánczky, Balázs Győrffy · Journal of Medical Internet Research · 2021 · 1.7K citations · Full text

PARP1-dependent Kinetics of Recruitment of MRE11 and NBS1 Proteins to Multiple DNA Damage Sites

Jean-François Haince, Darin McDonald, Amélie Rodrigue et al. · Journal of Biological Chemistry · 2007 · 590 citations · Full text

Parp1 Recruitment, Dna Damage, Radiation Effect +18

Pertuzumab plus trastuzumab for HER2-amplified metastatic colorectal cancer (MyPathway): an updated report from a multicentre, open-label, phase 2a, multiple basket study

Funda Meric‐Bernstam, Herbert I. Hurwitz, Kanwal Raghav et al. · The Lancet Oncology · 2019 · 543 citations

Medicine, Updated Report, Pathology +6

Nonhomologous end joining drives poly(ADP-ribose) polymerase (PARP) inhibitor lethality in homologous recombination-deficient cells

Anand G. Patel, Jann N. Sarkaria, Scott H. Kaufmann · Proceedings of the National Academy of Sciences · 2011 · 534 citations

Homologous Recombination-deficient Cells, Genome Instability, Parp Inhibition +13

Resistance to Trastuzumab in Breast Cancer

Paula R. Pohlmann, Ingrid A. Mayer, Ray Mernaugh · Clinical Cancer Research · 2009 · 495 citations · Full text