Concepedia

Methionine oxidation activates pyruvate kinase M2 to promote pancreatic cancer metastasis

Dan He, Huijin Feng, Belen Sundberg, Jiaxing Yang, Justin L. Powers, Alec H. Christian, John E. Wilkinson, Cian Monnin, Daina Avizonis, Craig J. Thomas,

Molecular Cell · 2022 · 74 citations · 74 references

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74

Linear Models and Empirical Bayes Methods for Assessing Differential Expression in Microarray Experiments

Gordon K. Smyth · Statistical Applications in Genetics and Molecular Biology · 2004 · 12K citations

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QuPath: Open source software for digital pathology image analysis

Peter Bankhead, Maurice B. Loughrey, José A. Fernández et al. · Scientific Reports · 2017 · 8.7K citations · Full text

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DNA targeting specificity of RNA-guided Cas9 nucleases

Patrick D. Hsu, David A. Scott, Joshua A. Weinstein et al. · Nature Biotechnology · 2013 · 4.9K citations · Full text

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Target-decoy search strategy for increased confidence in large-scale protein identifications by mass spectrometry

Joshua E. Elias, Steven P. Gygi · Nature Methods · 2007 · 4.1K citations

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The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth

Heather R. Christofk, Matthew G. Vander Heiden, Marian H. Harris et al. · Nature · 2008 · 2.8K citations

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