Concepedia

Parkinson’s disease-risk protein TMEM175 is a proton-activated proton channel in lysosomes

Meiqin Hu, Ping Li, Ce Wang, Xinghua Feng, Qi Geng, W. Chen, Matangi Marthi, Wenlong Zhang, Chenlang Gao, Whitney Reid,

Cell · 2022 · 247 citations · 72 references

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72

Genome engineering using the CRISPR-Cas9 system

F. Ann Ran, Patrick D. Hsu, Jason Wright et al. · Nature Protocols · 2013 · 11.7K citations · Full text

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Visualizing secretion and synaptic transmission with pH-sensitive green fluorescent proteins

Gero Miesenböck, Dino A. De Angelis, James E. Rothman · Nature · 1998 · 2.6K citations

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Pathological α-Synuclein Transmission Initiates Parkinson-like Neurodegeneration in Nontransgenic Mice

Kelvin C. Luk, Victoria Kehm, Jenna C. Carroll et al. · Science · 2012 · 2.6K citations

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Bafilomycins: a class of inhibitors of membrane ATPases from microorganisms, animal cells, and plant cells.

Emma Jean Bowman, Annette Siebers, Karlheinz Altendorf · Proceedings of the National Academy of Sciences · 1988 · 1.8K citations · Full text

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Lysosomal Proteolysis and Autophagy Require Presenilin 1 and Are Disrupted by Alzheimer-Related PS1 Mutations

Ju‐Hyun Lee, Wai Haung Yu, Asok Kumar et al. · Cell · 2010 · 1.2K citations · Full text

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