JACS Au · 2022 · 27 citations · 39 references
Life SciencesBiochemistryChemistryCatalysisEnzyme MechanismEnzymologyCatalytic MechanismsEnzyme KineticsEnzyme-substrate RecognitionHeme Redox ChemistryRedox CatalysisRedox EnzymesAlcohol DehydrogenationDealkylation ReactionsDehydrogenationDehydrogenation CatalysisHydroxylationHydroxylation ReactionsIron-catalyzed OxidationNon-heme Iron Enzymes
) was used as a second substrate analogue to study the alcohol dehydrogenation reaction to examine the involvement of the Y224 radical or Y68 radical in FtmOx1-catalysis, and again, the results from the verruculogen reaction are more consistent with the COX-like model.
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High-level semi-synthetic production of the potent antimalarial artemisinin
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Structure of a cephalosporin synthase
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