BSA-PEI Nanoparticle Mediated Efficient Delivery of CRISPR/Cas9 into MDA-MB-231 Cells

A Programmable Dual-RNA–Guided DNA Endonuclease in Adaptive Bacterial Immunity

Martin Jínek, Krzysztof Chylinski, Ines Fonfara et al. · Science · 2012 · 17.3K citations · Full text

Life Sciences, Microbiology, Molecular Biology +17

A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: polyethylenimine.

Otmane Boussif, Frank Lezoualc’h, Maria Antonietta Zanta et al. · Proceedings of the National Academy of Sciences · 1995 · 6.2K citations

Pharmacy, Biotechnology, Pharmaceutics +17

The Possible “Proton Sponge ” Effect of Polyethylenimine (PEI) Does Not Include Change in Lysosomal pH

Rikke Vicki Benjaminsen, Maria Ahlm Mattebjerg, Jonas R. Henriksen et al. · Molecular Therapy · 2012 · 716 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Direct Cytosolic Delivery of CRISPR/Cas9-Ribonucleoprotein for Efficient Gene Editing

Rubul Mout, Moumita Ray, Gülen Yesilbag Tonga et al. · ACS Nano · 2017 · 562 citations

Life Sciences, Genetics, Molecular Genetics +17

Targeted Delivery of CRISPR/Cas9‐Mediated Cancer Gene Therapy via Liposome‐Templated Hydrogel Nanoparticles

Zeming Chen, Fuyao Liu, Yanke Chen et al. · Advanced Functional Materials · 2017 · 296 citations

Pharmacy, Biotechnology, Oncology +17