Osteoclasts are essential for TNF-α–mediated joint destruction

Abstract

Nonstandard abbreviations used: rheumatoid arthritis (RA); matrix metalloproteinase (MMP); receptor activator of NF-B ligand (RANKL); human TNF-transgenic (hTNFtg); murine soluble TNF receptor type 1 (mTNF-R1); hematoxylin and