Concepedia

Targeting ABL-IRE1α Signaling Spares ER-Stressed Pancreatic β Cells to Reverse Autoimmune Diabetes

Shuhei Morita, S. Armando Villalta, Hannah C. Feldman, Ames C. Register, Wendy Rosenthal, Ingeborg T. Hoffmann‐Petersen, Morvarid Mehdizadeh, Rajarshi Ghosh, Likun Wang, Kevin Colon-Negron,

Cell Metabolism · 2017 · 181 citations · 41 references

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41

Mutation of the mouse klotho gene leads to a syndrome resembling ageing.

PubMed · 1997 · 66.6K citations

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XBP1 mRNA Is Induced by ATF6 and Spliced by IRE1 in Response to ER Stress to Produce a Highly Active Transcription Factor

Hiderou Yoshida, Toshie Matsui, Akira Yamamoto et al. · Cell · 2001 · 4.1K citations · Full text

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Endoplasmic Reticulum Stress Links Obesity, Insulin Action, and Type 2 Diabetes

Umut Özcan, Qiong Cao, Erkan Yılmaz et al. · Science · 2004 · 3.8K citations

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ASK1 is essential for endoplasmic reticulum stress-induced neuronal cell death triggered by expanded polyglutamine repeats

Hideki Nishitoh, Atsushi Matsuzawa, Kei Tobiume et al. · Genes & Development · 2002 · 1.3K citations · Full text

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Diabetes Mellitus and Exocrine Pancreatic Dysfunction in Perk−/− Mice Reveals a Role for Translational Control in Secretory Cell Survival

Heather P. Harding, Huiqing Zeng, Yuhong Zhang et al. · Molecular Cell · 2001 · 1.2K citations · Full text

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