Ames C. Register

Targeting ABL-IRE1α Signaling Spares ER-Stressed Pancreatic β Cells to Reverse Autoimmune Diabetes

Shuhei Morita, S. Armando Villalta, Hannah C. Feldman et al. · Cell Metabolism · 2017 · 177 citations · Full text

Insulin Signaling, Signal Transduction, Autoimmune Disease +8

A Combined Approach Reveals a Regulatory Mechanism Coupling Src’s Kinase Activity, Localization, and Phosphotransferase-Independent Functions

Ethan Ahler, Ames C. Register, Sujata Chakraborty et al. · Molecular Cell · 2019 · 73 citations · Full text

Signal Transduction, Molecular Physiology, Signaling Pathway +13

Divergent Modulation of Src-Family Kinase Regulatory Interactions with ATP-Competitive Inhibitors

Stephen E. Leonard, Ames C. Register, Ratika Krishnamurty et al. · ACS Chemical Biology · 2014 · 27 citations · Full text

Molecular Regulation, Molecular Biology, Analytical Ultracentrifugation +19

How ATP-Competitive Inhibitors Allosterically Modulate Tyrosine Kinases That Contain a Src-like Regulatory Architecture

Linglan Fang, Jessica Vilas-Boas, Sujata Chakraborty et al. · ACS Chemical Biology · 2020 · 26 citations · Full text

Modulate Tyrosine, Molecular Regulation, Molecular Biology +24

SH2-Catalytic Domain Linker Heterogeneity Influences Allosteric Coupling across the SFK Family

Ames C. Register, Stephen E. Leonard, Dustin J. Maly · Biochemistry · 2014 · 23 citations · Full text

Sfk Family Members, Molecular Biology, Signaling Pathway +21