Concepedia

UCE6, A new antitumor antibiotic with topoisomerase I mediated DNA cleavage activity, from actinomycetes.

Noboru Fujii, Yoshinori Yamashita, Shigeru Chiba, Youichi Uosaki, Yutaka Saitoh, YUKARI TUJI, HIROFUMI NAKANO

The Journal of Antibiotics · 1993 · 21 citations · 4 references

DOI

Concepts

References

4

DNA Topoisomerase I—Targeted Chemotherapy of Human Colon Cancer in Xenografts

Beppino C. Giovanella, John S. Stehlin, Monroe E. Wall et al. · Science · 1989 · 647 citations

, , +15

Modification of the hydroxylactone ring of camptothecin: inhibition of mammalian topoisomerase I and biological activity

Robert Hertzberg, Mary Jo Caranfa, Kenneth G. Holden et al. · Journal of Medicinal Chemistry · 1989 · 414 citations

, , +12

Induction of mammalian DNA topoisomerase I and II mediated DNA cleavage by saintopin, a new antitumor agent from fungus

Yoshinori Yamashita, Shozou Kawada, Noboru Fujii et al. · Biochemistry · 1991 · 119 citations

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DNA Topoisomerase Poisons As Antitumor Drugs

L. Liu · Annual Review of Biochemistry · 1989 · 79 citations

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