Indoxyl sulfate upregulates renal expression of ICAM-1 via production of ROS and activation of NF-κB and p53 in proximal tubular cells

Role of Organic Anion Transporters in the Tubular Transport of Indoxyl Sulfate and the Induction of its Nephrotoxicity

Atsushi Enomoto, Michio Takeda, Akihiro Tojo et al. · Journal of the American Society of Nephrology · 2002 · 291 citations

Indoxyl Sulfate Upregulates Expression of ICAM-1 and MCP-1 by Oxidative Stress-Induced NF-ĸB Activation

Zohra Tumur, Hidehisa Shimizu, Atsushi Enomoto et al. · American Journal of Nephrology · 2010 · 239 citations

Indoxyl sulphate promotes aortic calcification with expression of osteoblast-specific proteins in hypertensive rats

Ayinuer Adijiang, Shunsuke Goto, S. Uramoto et al. · Nephrology Dialysis Transplantation · 2008 · 219 citations

Progression of Glomerular Sclerosis in Experimental Uremic Rats by Administration of Indole, a Precursor of Indoxyl Sulfate

Toshimitsu Niwa, Mkhihito Ise, Takashi Miyazaki · American Journal of Nephrology · 1994 · 177 citations

Indole Administration, Glomerulonephritis, Experimental Uremic Rats +15

NF-κB plays an important role in indoxyl sulfate-induced cellular senescence, fibrotic gene expression, and inhibition of proliferation in proximal tubular cells

Hidehisa Shimizu, Dilinaer Bolati, Ayinuer Adijiang et al. · American Journal of Physiology-Cell Physiology · 2011 · 161 citations

Immunology, Renal Inflammation, Pathology +21