Hidehisa Shimizu

Indoxyl Sulfate Upregulates Expression of ICAM-1 and MCP-1 by Oxidative Stress-Induced NF-ĸB Activation

Zohra Tumur, Hidehisa Shimizu, Atsushi Enomoto et al. · American Journal of Nephrology · 2010 · 241 citations

Life Sciences, Molecular Biology, Pharmacology +17

NF-κB plays an important role in indoxyl sulfate-induced cellular senescence, fibrotic gene expression, and inhibition of proliferation in proximal tubular cells

Hidehisa Shimizu, Dilinaer Bolati, Ayinuer Adijiang et al. · American Journal of Physiology-Cell Physiology · 2011 · 169 citations

Life Sciences, Cell Biology, Pharmacology +14

Indoxyl sulfate upregulates renal expression of MCP-1 via production of ROS and activation of NF-κB, p53, ERK, and JNK in proximal tubular cells

Hidehisa Shimizu, Dilinaer Bolati, Yukihiro Higashiyama et al. · Life Sciences · 2012 · 148 citations

Life Sciences, Cell Biology, Nephrology +9

The Leishmania Surface Protease GP63 Cleaves Multiple Intracellular Proteins and Actively Participates in p38 Mitogen-activated Protein Kinase Inactivation

Maxime Hallé, María Adelaida Gómez, Matthew Stuible et al. · Journal of Biological Chemistry · 2008 · 138 citations · Full text

Life Sciences, Infectious Diseases, Molecular Biology +17

Indoxyl sulfate, a uremic toxin, downregulates renal expression of Nrf2 through activation of NF-κB

Dilinaer Bolati, Hidehisa Shimizu, Maimaiti Yisireyili et al. · BMC Nephrology · 2013 · 129 citations · Full text

Medicine, Nephrology, Pharmacology +17