Amelioration of inflammatory arthritis by targeting the pre-ligand assembly domain of tumor necrosis factor receptors

Transgenic mice expressing human tumour necrosis factor: a predictive genetic model of arthritis.

Jeanne Keffer, Lesley Probert, Haris Cazlaris et al. · The EMBO Journal · 1991 · 1.7K citations · Full text

Life Sciences, Genetics, Immunology +14

Treatment of rheumatoid arthritis with tumor necrosis factor inhibitors may predispose to significant increase in tuberculosis risk: A multicenter active‐surveillance report

Juan J. Gómez‐Reino, Loreto Carmona, Vicente Rodríguez Valverde et al. · Arthritis & Rheumatism · 2003 · 1K citations

Medicine, Internal Medicine, Pharmacotherapy +15

Anti-tumor necrosis factor ameliorates joint disease in murine collagen-induced arthritis.

Richard Williams, Marc Feldmann, R N Maini · Proceedings of the National Academy of Sciences · 1992 · 986 citations

Medicine, Immunology, Pathobiology +12

Lymphoma in rheumatoid arthritis: The effect of methotrexate and anti–tumor necrosis factor therapy in 18,572 patients

Frederick Wolfe, Kaleb Michaud · Arthritis & Rheumatism · 2004 · 646 citations

Medicine, Immunology, Cancer Epidemiology +12

Fas Preassociation Required for Apoptosis Signaling and Dominant Inhibition by Pathogenic Mutations

Richard M. Siegel, John K. Frederiksen, David A. Zacharias et al. · Science · 2000 · 645 citations

Life Sciences, Cell Biology, Molecular Biology +17