Francis Ka-Ming Chan

Phosphorylation-Driven Assembly of the RIP1-RIP3 Complex Regulates Programmed Necrosis and Virus-Induced Inflammation

Young-Sik Cho, Sreerupa Challa, David Moquin et al. · Cell · 2009 · 2.4K citations · Full text

Inflammation, Phosphorylation-driven Assembly, Viral Replication +9

The RIP1/RIP3 Necrosome Forms a Functional Amyloid Signaling Complex Required for Programmed Necrosis

Jixi Li, Thomas J. McQuade, Ansgar B. Siemer et al. · Cell · 2012 · 1.2K citations · Full text

Inflammation, Alzheimer's Disease, Cell Death +9

Fas Preassociation Required for Apoptosis Signaling and Dominant Inhibition by Pathogenic Mutations

Richard M. Siegel, John K. Frederiksen, David A. Zacharias et al. · Science · 2000 · 641 citations

Mitophagy, Genetics, Apoptosis +21

Inherited Human Caspase 10 Mutations Underlie Defective Lymphocyte and Dendritic Cell Apoptosis in Autoimmune Lymphoproliferative Syndrome Type II

Jin Wang, Lixin Zheng, Adrian A. Lobito et al. · Cell · 1999 · 632 citations · Full text

Immunogenetics, Autoimmune Disease, Immunology +9

RIP3 Induces Apoptosis Independent of Pronecrotic Kinase Activity

Pratyusha Mandal, Scott B. Berger, Sirika Pillay et al. · Molecular Cell · 2014 · 593 citations · Full text

Cell Regulation, Pronecrotic Kinase Activity, Receptor Tyrosine Kinase +6