Lab on a Chip · 2008 · 247 citations · 21 references
EngineeringBioengineeringMaterials ScienceMicroelectromechanical SystemsMicrofabricationSurface EngineeringMicrofabrication ProcessesMicrofluidic Device FabricationMicrofluidic DevicesMicrofluidic SystemsMicrofluidicsSoft LithographyMicro-patterned SurfacesMicrofluidic Device DesignMicrofluidic Droplet GenerationMicrofluidic FabricationMicrofluidic FlowMicrofluidic PatterningPressure ResistanceSurface Coating Technologies
We present how to make and assemble micro-patterned stickers (microPS) to construct high performance plastic microfluidic devices in a few minutes. We take advantage of soft UV imprint techniques to tailor the geometry, the mechanical properties, and the surface chemistry of 2D and 3D microfluidic circuits. The resulting microfluidic stickers substantially overcome the actual performance of the very popular PDMS devices for a wide range of applications, while sharing their celebrated fast and easy processing. To highlight the intrinsic advantages of this method, three important applications are detailed: (i) we show that both aqueous and organic droplets can be produced and stored in stickers without any specific surface coating. (ii) We report on the outstanding pressure resistance of the microPS, which open the way to the transport of viscous complex fluids. (iii) Finally, a simple design strategy is proposed to generate complex flow patterns in interconnected stacks of microPS.
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