N6-methyladenosine-modified TRAF1 promotes sunitinib resistance by regulating apoptosis and angiogenesis in a METTL14-dependent manner in renal cell carcinoma - Concepedia

Concepedia

Publication | Open Access

N6-methyladenosine-modified TRAF1 promotes sunitinib resistance by regulating apoptosis and angiogenesis in a METTL14-dependent manner in renal cell carcinoma

DOI Full Paper Access

96

Citations

36

References

2022

Year

Yuanlei Chen, Zeyi Lu, Chao Qi, Chenhao Yu, Yang Li, Huan Wang, Ruyue Wang, Wenqin Luo, Danyang Shen, Lifeng Ding,

Molecular Cancer

Abstract

Overexpression of TRAF1 promotes sunitinib resistance by modulating apoptotic and angiogenic pathways in a METTL14-dependent manner. Targeting TRAF1 and its pathways may be a novel pharmaceutical intervention for sunitinib-treated patients.

References

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