Dehydroepiandrosterone exacerbates nigericin-induced abnormal autophagy and pyroptosis via GPER activation in LPS-primed macrophages

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

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Mtor Regulate Autophagy, Mitophagy, Cell Autophagy +10

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Inflammation, Signal Transduction, Signaling Pathway +12

A role for mitochondria in NLRP3 inflammasome activation

Rongbin Zhou, Amir S. Yazdi, Philippe Menu et al. · Nature · 2010 · 5.3K citations

Inflammation, Mitochondrial Function, Cell Death +7

NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals

Peter Duewell, Hajime Kono, Katey J. Rayner et al. · Nature · 2010 · 3.8K citations · Full text

Inflammation, Signal Transduction, Oxysterol +12

Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores

Xing Liu, Zhibin Zhang, Jianbin Ruan et al. · Nature · 2016 · 3.1K citations · Full text

Inflammation, Apoptosis, Cell Death +7