Concepedia

Assessment of a Plasma Amyloid Probability Score to Estimate Amyloid Positron Emission Tomography Findings Among Adults With Cognitive Impairment

Yan Hu, Kristopher M. Kirmess, Matthew R. Meyer, Gil D. Rabinovici, Constantine Gatsonis, Barry A. Siegel, Rachel A. Whitmer, Charles Apgar, Lucy Hanna, Michio Kanekiyo,

JAMA Network Open · 2022 · 125 citations · 23 references

DOIFull text

Open access

Abstract

These findings suggest that this blood biomarker test could allow for distinguishing individuals with brain amyloid-positive PET findings from individuals with amyloid-negative PET findings and serve as an aid for Alzheimer disease diagnosis.

References

23

Amyloid Oligomers Exacerbate Tau Pathology in a Mouse Model of Tauopathy

Maj-Linda B. Selenica, Milene L. Brownlow, Jeffy P. Jimenez et al. · Neurodegenerative Diseases · 2012 · 10.4K citations · Full text

High performance plasma amyloid-β biomarkers for Alzheimer’s disease

Akinori Nakamura, Naoki Kaneko, Victor L. Villemagne et al. · Nature · 2018 · 1.6K citations · Full text

, , +6

Population estimate of people with clinical Alzheimer's disease and mild cognitive impairment in the United States (2020–2060)

Kumar B. Rajan, Jennifer Weuve, Lisa L. Barnes et al. · Alzheimer s & Dementia · 2021 · 1.1K citations · Full text

, , +24

Accuracy of the Clinical Diagnosis of Alzheimer Disease at National Institute on Aging Alzheimer Disease Centers, 2005–2010

Thomas G. Beach, Sarah E. Monsell, Leslie E. Phillips et al. · Journal of Neuropathology & Experimental Neurology · 2012 · 1.1K citations · Full text

High-precision plasma β-amyloid 42/40 predicts current and future brain amyloidosis

Suzanne E. Schindler, James G. Bollinger, Vitaliy Ovod et al. · Neurology · 2019 · 851 citations · Full text