Loss of ERdj5 exacerbates oxidative stress in mice with alcoholic liver disease via suppressing Nrf2

Mouse model of chronic and binge ethanol feeding (the NIAAA model)

Adeline Bertola, Stephanie Mathews, Sung Hwan Ki et al. · Nature Protocols · 2013 · 1.2K citations · Full text

Medicine, Neurobiology, Neuroscience +12

Imaging of neutral lipids by oil red O for analyzing the metabolic status in health and disease

Annika Mehlem, Carolina E. Hagberg, Lars Muhl et al. · Nature Protocols · 2013 · 894 citations

Life Sciences, Biochemistry, Biomedical Imaging +15

Defining human ERAD networks through an integrative mapping strategy

John C. Christianson, James A. Olzmann, Thomas A. Shaler et al. · Nature Cell Biology · 2011 · 509 citations · Full text

Social Sciences, Human Geography, Knowledge Networks +4

ERdj5 Is Required as a Disulfide Reductase for Degradation of Misfolded Proteins in the ER

Ryo Ushioda, Jun Hoseki, Kazutaka Araki et al. · Science · 2008 · 397 citations

Life Sciences, Cell Biology, Molecular Biology +16

Redox-regulated Turnover of Nrf2 Is Determined by at Least Two Separate Protein Domains, the Redox-sensitive Neh2 Degron and the Redox-insensitive Neh6 Degron

Michael McMahon, Nerys Thomas, Ken Itoh et al. · Journal of Biological Chemistry · 2004 · 395 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17