Systems pharmacology, proteomics and in vivo studies identification of mechanisms of cerebral ischemia injury amelioration by Huanglian Jiedu Decoction

limma powers differential expression analyses for RNA-sequencing and microarray studies

Matthew E. Ritchie, Belinda Phipson, Di Wu et al. · Nucleic Acids Research · 2015 · 43K citations · Full text

Life Sciences, Bioinformatics, Molecular Biology +17

STRING v11: protein–protein association networks with increased coverage, supporting functional discovery in genome-wide experimental datasets

Damian Szklarczyk, Annika L. Gable, David Lyon et al. · Nucleic Acids Research · 2018 · 19.2K citations · Full text

Life Sciences, Bioinformatics, Systems Biology +17

NCBI GEO: archive for functional genomics data sets—update

Tanya Barrett, Stephen E. Wilhite, Pierre Ledoux et al. · Nucleic Acids Research · 2012 · 10.8K citations · Full text

Life Sciences, Bioinformatics, Geoinformatics +16

Universal sample preparation method for proteome analysis

Jacek R. Wiśniewski, Alexandre Zougman, Nagarjuna Nagaraj et al. · Nature Methods · 2009 · 8.7K citations

Life Sciences, Biochemistry, Molecular Biology +14

cytoHubba: identifying hub objects and sub-networks from complex interactome

Chia-Hao Chin, Shu-Hwa Chen, Hsin-Hung Wu et al. · BMC Systems Biology · 2014 · 6.8K citations · Full text

Life Sciences, Bioinformatics, Biology +15