EV-T synergizes with AZD5582 to overcome TRAIL resistance through concomitant suppression of cFLIP, MCL-1, and IAPs in hepatocarcinoma

Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries

Hyuna Sung, Jacques Ferlay, Rebecca L. Siegel et al. · CA A Cancer Journal for Clinicians · 2021 · 112.5K citations · Full text

Medicine, Oncology, Cancer Epidemiology +16

Tumoricidal activity of tumor necrosis factor–related apoptosis–inducing ligand in vivo

Henning Walczak, Robert E. Miller, K. Ariail et al. · Nature Medicine · 1999 · 2.5K citations

Life Sciences, Oncology, Pharmacology +12

Safety and antitumor activity of recombinant soluble Apo2 ligand

Avi Ashkenazi, Roger Pai, Sharon Fong et al. · Journal of Clinical Investigation · 1999 · 2.2K citations · Full text

Medicine, Oncology, Pharmacology +17

Induction of Apoptosis by Apo-2 Ligand, a New Member of the Tumor Necrosis Factor Cytokine Family

Robert Pitti, Scot A. Marsters, Siegfried Ruppert et al. · Journal of Biological Chemistry · 1996 · 1.8K citations · Full text

Life Sciences, Immunology, Molecular Biology +17

Exosome-mediated delivery of siRNA in vitro and in vivo

Samir EL Andaloussi, Yi Lee, Samira Lakhal‐Littleton et al. · Nature Protocols · 2012 · 611 citations

Pharmacy, Molecular Pharmaceutics, Pharmaceutics +11