Concepedia

Exosome-mediated delivery of siRNA in vitro and in vivo

Samir EL Andaloussi, Yi Lee, Samira Lakhal‐Littleton, Jinghuan Li, Yiqi Seow, Chris Gardiner, Lydia Alvarez‐Erviti, Ian L. Sargent, Matthew J. A. Wood

Nature Protocols · 2012 · 611 citations · 16 references

DOI

Concepts

References

16

Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells

Hadi Valadi, Karin M. Ekström, Apostolos Bossios et al. · Nature Cell Biology · 2007 · 12.8K citations

, , +12

Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes

Lydia Alvarez‐Erviti, Yiqi Seow, HaiFang Yin et al. · Nature Biotechnology · 2011 · 4.8K citations

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A Truncated HIV-1 Tat Protein Basic Domain Rapidly Translocates through the Plasma Membrane and Accumulates in the Cell Nucleus

Éric Vivès, Priscille Brodin, Bernard Lebleu · Journal of Biological Chemistry · 1997 · 2.4K citations · Full text

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Unidirectional transfer of microRNA-loaded exosomes from T cells to antigen-presenting cells

Marı́a Mittelbrunn, Cristina Gutiérrez‐Vázquez, Carolina Villarroya‐Beltri et al. · Nature Communications · 2011 · 1.8K citations · Full text

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Embryonic stem cell-derived microvesicles reprogram hematopoietic progenitors: evidence for horizontal transfer of mRNA and protein delivery

Janina Ratajczak, Katarzyna Miękus, Magda Kucia et al. · Leukemia · 2006 · 1.6K citations

, , +17