Concepedia

Publication | Open Access

Imipridones affect tumor bioenergetics and promote cell lineage differentiation in diffuse midline gliomas

DOIFull Paper Access

91

Citations

22

References

2022

Year

Justyna M. Przystal, Chiara Cosentino, Sridevi Yadavilli, Jie Zhang, Sandra Laternser, Erin R. Bonner, Rachna Prasad, Adam Dawood, Nina Lobeto, Wai Chin Chong,
Neuro-Oncology

Abstract

Targeting mitochondrial metabolism and ISR activation effectively impairs DMG tumorigenicity. These results supported the initiation of two pediatric clinical trials (NCT05009992, NCT04732065).

References

YearCitations

Page 1