Concepedia

San-Wu-Huang-Qin decoction attenuates tumorigenesis and mucosal barrier impairment in the AOM/DSS model by targeting gut microbiome

Yelu Zhou, Yuanyuan Feng, Rong Cen, Xinxin Hou, Hao Yu, Jian Sun, Lihong Zhou, Qing Ji, Ling Zhao, Yan Wang,

Phytomedicine · 2022 · 39 citations · 52 references

DOIFull text

Open access

Abstract

We demonstrated that the SWHQ effectively inhibited tumorigenesis and protect mucosal barrier in CRC at least partially by targeting gut microbiota. This study provides scientific basis for the clinical usage of SWHQ in CRC intervention and prevention.

References

52

Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries

Hyuna Sung, Jacques Ferlay, Rebecca L. Siegel et al. · CA A Cancer Journal for Clinicians · 2021 · 109.5K citations · Full text

Metabolic Endotoxemia Initiates Obesity and Insulin Resistance

Patrice D. Cani, Jacques Amar, Miguel A. Iglesias et al. · Diabetes · 2007 · 6.2K citations · Full text

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Cross-talk between <i>Akkermansia muciniphila</i> and intestinal epithelium controls diet-induced obesity

Amandine Everard, Clara Belzer, Lucie Geurts et al. · Proceedings of the National Academy of Sciences · 2013 · 4.2K citations · Full text

Supplementation with Akkermansia muciniphila in overweight and obese human volunteers: a proof-of-concept exploratory study

Clara Depommier, Amandine Everard, Céline Druart et al. · Nature Medicine · 2019 · 2.1K citations · Full text

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A purified membrane protein from Akkermansia muciniphila or the pasteurized bacterium improves metabolism in obese and diabetic mice

Hubert Plovier, Amandine Everard, Céline Druart et al. · Nature Medicine · 2016 · 2K citations · Full text

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