Stabilization of RyR2 maintains right ventricular function, reduces the development of ventricular arrhythmias, and improves prognosis in pulmonary hypertension

ASPIRE registry: Assessing the Spectrum of Pulmonary hypertension Identified at a REferral centre

Judith Hurdman, Robin Condliffe, Charlie Elliot et al. · European Respiratory Journal · 2011 · 457 citations · Full text

Medicine, Clinical Sciences, Internal Medicine +10

SparkMaster: automated calcium spark analysis with ImageJ

Eckard Picht, Aleksey V. Zima, Lothar A. Blatter et al. · American Journal of Physiology-Cell Physiology · 2007 · 329 citations

Natural Sciences, Biophysics, Cell Biology +14

Structural basis for the gating mechanism of the type 2 ryanodine receptor RyR2

Wei Peng, Huaizong Shen, Jianping Wu et al. · Science · 2016 · 282 citations

Natural Sciences, Biophysics, Cell Biology +17

FKBP12.6-Mediated Stabilization of Calcium-Release Channel (Ryanodine Receptor) as a Novel Therapeutic Strategy Against Heart Failure

Masafumi Yano, Shigeki Kobayashi, Masateru Kohno et al. · Circulation · 2003 · 260 citations

Medicine, Cardiology, Pharmacology +17

Dantrolene, a Therapeutic Agent for Malignant Hyperthermia, Markedly Improves the Function of Failing Cardiomyocytes by Stabilizing Interdomain Interactions Within the Ryanodine Receptor

Shigeki Kobayashi, Masafumi Yano, Takeshi Suetomi et al. · Journal of the American College of Cardiology · 2009 · 187 citations · Full text

Medicine, Cardiology, Pharmacology +17