Blood Circulatory Level of Seven Sirtuins in Alzheimer’s Disease: Potent Biomarker Based on Translational Research

Clinical diagnosis of Alzheimer's disease

Guy M. McKhann, David A. Drachman, Marshall Folstein et al. · Neurology · 1984 · 28K citations · Full text

Medicine, Geriatric Medicine, Neurology +16

Ultrastructural Characterization of the Lower Motor System in a Mouse Model of Krabbe Disease

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Medicine, Neurobiology, Neuroscience +17

SIRT6 is a histone H3 lysine 9 deacetylase that modulates telomeric chromatin

Eriko Michishita, Ronald A. McCord, Elisabeth Berber et al. · Nature · 2008 · 1.1K citations

Life Sciences, Genetics, Molecular Biology +14

The human silent information regulator (Sir)2 homologue hSIRT3 is a mitochondrial nicotinamide adenine dinucleotide–dependent deacetylase

Björn Schwer, Brian J. North, Roy A. Frye et al. · The Journal of Cell Biology · 2002 · 600 citations · Full text

Life Sciences, Biochemistry, Genetics +12

Sirtuin 1 Reduction Parallels the Accumulation of Tau in Alzheimer Disease

Carl Julien, Cyntia Tremblay, Vincent Émond et al. · Journal of Neuropathology & Experimental Neurology · 2008 · 475 citations · Full text

Life Sciences, Molecular Biology, Neuroscience +15