Curcumin mitigates aflatoxin B1-induced liver injury via regulating the NLRP3 inflammasome and Nrf2 signaling pathway

Hepatocyte pyroptosis and release of inflammasome particles induce stellate cell activation and liver fibrosis

Susanne Gaul, Aleksandra Leszczynska, Fernando Alegre et al. · Journal of Hepatology · 2020 · 544 citations · Full text

Veterinary Medicine, Cell Biology, Pathology +17

Scaffolding of Keap1 to the actin cytoskeleton controls the function of Nrf2 as key regulator of cytoprotective phase 2 genes

Moon-Il Kang, Akira Kobayashi, Nobunao Wakabayashi et al. · Proceedings of the National Academy of Sciences · 2004 · 532 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +13

N-GSDMD trafficking to neutrophil organelles facilitates IL-1β release independently of plasma membrane pores and pyroptosis

Mausita Karmakar, Martin Minns, Elyse Noelani Greenberg et al. · Nature Communications · 2020 · 446 citations · Full text

Life Sciences, Cell Biology, Immunology +17

NEK7 interacts with NLRP3 to modulate the pyroptosis in inflammatory bowel disease via NF-κB signaling

Xueliang Chen, Ganglei Liu, Yuanyuan Yuan et al. · Cell Death and Disease · 2019 · 388 citations · Full text

Life Sciences, Immunology, Pathobiology +14

Detection of elevated reactive oxygen species level in cultured rat hepatocytes treated with aflatoxin B1

Han‐Ming Shen, Chenyang Shi, Yi Shen et al. · Free Radical Biology and Medicine · 1996 · 307 citations

Pharmacy, Biochemistry, Toxicology +16