CXCR4-guided liposomes regulating hypoxic and immunosuppressive microenvironment for sorafenib-resistant tumor treatment

PD-1 expression by tumour-associated macrophages inhibits phagocytosis and tumour immunity

Sydney Gordon, Roy L. Maute, Ben W. Dulken et al. · Nature · 2017 · 2.2K citations · Full text

Inflammation, Cancer Immunosurveillance, Pd-1 Expression +9

Ultrasound Triggered Tumor Oxygenation with Oxygen-Shuttle Nanoperfluorocarbon to Overcome Hypoxia-Associated Resistance in Cancer Therapies

Xuejiao Song, Liangzhu Feng, Chao Liang et al. · Nano Letters · 2016 · 575 citations

Biomedical Acoustics, Engineering, Biomedical Engineering +20

Disruption of tumour-associated macrophage trafficking by the osteopontin-induced colony-stimulating factor-1 signalling sensitises hepatocellular carcinoma to anti-PD-L1 blockade

Ying Zhu, Jing Yang, Da Xu et al. · Gut · 2019 · 402 citations

Inhibition of CSF-1 Receptor Improves the Antitumor Efficacy of Adoptive Cell Transfer Immunotherapy

Stephen Mok, Richard C. Koya, Christopher Tsui et al. · Cancer Research · 2013 · 311 citations · Full text

Cell Therapy, Tyrosine Kinase, Immunology +24

Hypoxia-mediated sorafenib resistance can be overcome by EF24 through Von Hippel-Lindau tumor suppressor-dependent HIF-1α inhibition in hepatocellular carcinoma

Yingjian Liang, Tongsen Zheng, Ruipeng Song et al. · Hepatology · 2013 · 292 citations