Richard C. Koya

Melanomas acquire resistance to B-RAF(V600E) inhibition by RTK or N-RAS upregulation

Ramin Nazarian, Hubing Shi, Qi Wang et al. · Nature · 2010 · 2.2K citations

Medicine, Cancer Biology, Oncology +11

<i>RAS</i> Mutations in Cutaneous Squamous-Cell Carcinomas in Patients Treated with BRAF Inhibitors

Fei Su, Amaya Virós, Carla Milagre et al. · New England Journal of Medicine · 2012 · 1K citations · Full text

Medicine, Dermatology, Oncology +13

Acquired Resistance and Clonal Evolution in Melanoma during BRAF Inhibitor Therapy

Hubing Shi, Willy Hugo, Xiangju Kong et al. · Cancer Discovery · 2013 · 986 citations · Full text

Medicine, Genetics, Oncology +17

Melanoma whole-exome sequencing identifies V600EB-RAF amplification-mediated acquired B-RAF inhibitor resistance

Hubing Shi, Gatien Moriceau, Xiangju Kong et al. · Nature Communications · 2012 · 620 citations · Full text

Medicine, Genetics, Oncology +14

Improved antitumor activity of immunotherapy with BRAF and MEK inhibitors in <i>BRAF</i> ^<i>V600E</i> melanoma

Siwen Hu‐Lieskovan, Stephen Mok, Blanca Homet Moreno et al. · Science Translational Medicine · 2015 · 568 citations · Full text

Medicine, Immunology, Oncology +14