Concepedia

Müller glia-derived exosomal miR-9-3p promotes angiogenesis by restricting sphingosine-1-phosphate receptor S1P1 in diabetic retinopathy

Yu Liu, Qin Yang, Haixin Fu, Jingfan Wang, Songtao Yuan, Xinsheng Li, Ping Xie, Zizhong Hu, Qinghuai Liu

Molecular Therapy — Nucleic Acids · 2021 · 63 citations · 49 references

DOIFull text

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Concepts

Abstract

coding sequence, which subsequently activated VEGFR2 phosphorylation and internalization in the presence or absence of exogenous VEGF-A. We successfully orchestrated the dynamic crosstalk between retinal Müller glia cells and endothelial cells in pathological condition, which may provide a novel biomarker or promising therapeutic agents for the treatment of diabetic retinopathy.

References

49

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