M2-polarized tumor-associated macrophages promoted epithelial–mesenchymal transition in pancreatic cancer cells, partially through TLR4/IL-10 signaling pathway

Chaoying Liu, Juan-Ying Xu, Xiaoyan Shi, +4

Laboratory Investigation

Amelioration of progressive renal injury by genetic manipulation of <i>Klotho</i> gene

Yoshisuke Haruna, Naoki Kashihara, Minoru Satoh, +6

Proceedings of the National Academy of Sciences

Protection of Mcc950 against high-glucose-induced human retinal endothelial cell dysfunction

Yi Zhang, Xuehua Lv, Zizhong Hu, +5

Cell Death and Disease

Protective effect of alpha-mangostin against oxidative stress induced-retinal cell death

Yuan Fang, Su Tu, Xiaorong Qiu, +7

Scientific Reports

Chronic photo-oxidative stress and subsequent MCP-1 activation as causative factors for age-related macular degeneration

Mihoko Suzuki, Motokazu Tsujikawa, Hiroyuki Itabe, +9

Journal of Cell Science

Ocular DiseaseLipid PeroxidationAge-related Macular DegenerationOptogeneticsRedox Biology +14

Atrogin-1/MAFbx Enhances Simulated Ischemia/Reperfusion-induced Apoptosis in Cardiomyocytes through Degradation of MAPK Phosphatase-1 and Sustained JNK Activation

Ping Xie, Shubin Guo, Yongna Fan, +3

Journal of Biological Chemistry

Cardiac MuscleHeart FailureApoptosisCell DeathOxidative Stress +19

Single-Cell Transcriptomics Reveals Novel Role of Microglia in Fibrovascular Membrane of Proliferative Diabetic Retinopathy

Zizhong Hu, Xiying Mao, Mingkang Chen, +8

Diabetes

Ocular DiseaseImmunologyNeuroinflammationInflammationRetinal Hemorrhage +17

Rap1b GTPase Ameliorates Glucose-Induced Mitochondrial Dysfunction

Lin Sun, Ping Xie, Jun Wada, +7

Journal of the American Society of Nephrology

Niemann-Pick C1-Like 1 deletion in mice prevents high-fat diet-induced fatty liver by reducing lipogenesis

Lin Jia, Yinyan Ma, Shunxing Rong, +6

Journal of Lipid Research

Retinal Neurodegeneration in db/db Mice at the Early Period of Diabetes

Qin Yang, Yidan Xu, Ping Xie, +5

Journal of Ophthalmology

Ocular DiseaseImmunologyRetinal NeurodegenerationDb/db MiceDiabetic Retinopathy +19