Hydrogen Attenuated Inflammation Response and Oxidative in Hypoxic Ischemic Encephalopathy via Nrf2 Mediated the Inhibition of NLRP3 and NF-κB

Global, regional, and national causes of child mortality in 2000–13, with projections to inform post-2015 priorities: an updated systematic analysis

Li Liu, Shefali Oza, Daniel Hogan et al. · The Lancet · 2014 · 3.2K citations

Public Health, Child Health, Pediatrics +16

Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals

Ikuroh Ohsawa, Masahiro Ishikawa, Kumiko Takahashi et al. · Nature Medicine · 2007 · 2.5K citations

Life Sciences, Biochemistry, Pharmacology +13

Brusatol enhances the efficacy of chemotherapy by inhibiting the Nrf2-mediated defense mechanism

Dong‐Mei Ren, Nicole Villeneuve, Tao Jiang et al. · Proceedings of the National Academy of Sciences · 2011 · 652 citations

Medicine, Oncology, Pharmacology +14

Systemic inflammation disrupts the developmental program of white matter

Géraldine Favrais, Yohan van de Looij, Bobbi Fleiss et al. · Annals of Neurology · 2011 · 403 citations

Medicine, Neurobiology, Neuroscience +17

Neuroprotective effects of hydrogen saline in neonatal hypoxia–ischemia rat model

Jianmei Cai, Zhimin Kang, Kan Liu et al. · Brain Research · 2008 · 226 citations

Medicine, Neurobiology, Neuroscience +14