Gut Microbiota and Serum Metabolic Signatures of High-Fat-Induced Bone Loss in Mice

Abstract

These findings indicated that the alternations of GM and serum metabolites were related to HFD-induced bone loss, which might provide new insights into explain the occurrence and development of HFD-related osteoporosis. The regulatory effects of GM and metabolites associated with HFD on bone homeostasis required further exploration.