Novel chemical inhibitor against SOD1 misfolding and aggregation protects neuron-loss and ameliorates disease symptoms in ALS mouse model

References

Page 1

	Year	Citations
Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis D.R. Rosen, Teepu Siddique, David T. Patterson, Nature Neurodegenerative DiseasesAmyotrophic Lateral SclerosisNeurological DisorderGeneticsMolecular Biology	1993	7K
Motor Neuron Degeneration in Mice that Express a Human Cu,Zn Superoxide Dismutase Mutation Mark E. Gurney, Haifeng Pu, Arlene Y. Chiu, Science	1994	4.1K
Lewy bodies in grafted neurons in subjects with Parkinson's disease suggest host-to-graft disease propagation Jiayi Li, Elisabet Englund, Janice L. Holton, Nature Medicine Host-to-graft Disease PropagationExperimental NeuropathologyLewy BodiesNeurologyNeuroscience	2008	1.8K
Transmission and spreading of tauopathy in transgenic mouse brain Florence Clavaguera, Tristan Bolmont, R. Anthony Crowther, Nature Cell Biology Knockout MouseNeurodegenerative DiseasesXenotransplantationTransgenic Mouse ModelsDegenerative Pathology	2009	1.8K
Lewy body–like pathology in long-term embryonic nigral transplants in Parkinson's disease Jeffrey H. Kordower, Yaping Chu, Robert A. Hauser, Nature Medicine Neurodegenerative DiseasesParkinson DiseaseNeuroscienceNeurologyLewy Body–like Pathology	2008	1.7K
ALS-Linked SOD1 Mutant G85R Mediates Damage to Astrocytes and Promotes Rapidly Progressive Disease with SOD1-Containing Inclusions Lucie Bruijn, Mark W. Bêcher, Michael K. Lee, Neuron	1997	1.3K
Human α-synuclein-harboring familial Parkinson's disease-linked Ala-53 → Thr mutation causes neurodegenerative disease with α-synuclein aggregation in transgenic mice Michael K. Lee, Wanda L.H. Stirling, Yanqun Xu, Proceedings of the National Academy of Sciences	2002	833
α-Synuclein propagates from mouse brain to grafted dopaminergic neurons and seeds aggregation in cultured human cells Christian Hansen, Élodie Angot, Ann‐Louise Bergström, Journal of Clinical Investigation	2011	819
RIPK1 mediates axonal degeneration by promoting inflammation and necroptosis in ALS Yasushi Ito, Dimitry Ofengeim, Ayaz Najafov, Science ImmunologyCell DeathNeuroinflammationInflammationAutophagy	2016	591
Degeneration and impaired regeneration of gray matter oligodendrocytes in amyotrophic lateral sclerosis Shin Hyeok Kang, Ying Li, Masahiro Fukaya, Nature Neuroscience Gray Matter OligodendrocytesNeurodegenerative DiseasesNeuroregenerationAmyotrophic Lateral SclerosisDegenerative Pathology	2013	568

Page 1