Lewy bodies in grafted neurons in subjects with Parkinson's disease suggest host-to-graft disease propagation

Jiayi Li, Elisabet Englund, Janice L. Holton, +11

Nature Medicine

Host-to-graft Disease PropagationExperimental NeuropathologyLewy BodiesNeurologyNeuroscience +5

Direct evidence of Parkinson pathology spread from the gastrointestinal tract to the brain in rats

Staffan Holmqvist, Oldriska Chutna, Luc Bousset, +7

Acta Neuropathologica

NeuroanatomyExperimental NeuropathologyGastroenterologyPathologyParkinson Pathology Spread +8

α-Synuclein propagates from mouse brain to grafted dopaminergic neurons and seeds aggregation in cultured human cells

Christian Hansen, Élodie Angot, Ann‐Louise Bergström, +9

Journal of Clinical Investigation

Transplantation of Human Embryonic Stem Cell-Derived Cells to a Rat Model of Parkinson's Disease: Effect of In Vitro Differentiation on Graft Survival and Teratoma Formation

Anke Brederlau, Ana Sofia Correia, Sergey V. Anisimov, +15

Stem Cells

Impaired meningeal lymphatic drainage in patients with idiopathic Parkinson’s disease

Xuebing Ding, Xinxin Wang, Danhao Xia, +16

Nature Medicine

Parkinson DiseaseLymphatic SystemNeurologyLymphatic DiseaseNeuropathology +2

Orexin loss in Huntington's disease

Åsa Petersén, Joana Gil‐Mohapel, Marion L. C. Maat–Schieman, +12

Human Molecular Genetics

Dramatic AtrophyOrexin NeuronsOrexin LossGeneticsPhysiology +9

Characterization of Lewy body pathology in 12‐ and 16‐year‐old intrastriatal mesencephalic grafts surviving in a patient with Parkinson's disease

Jiayi Li, Elisabet Englund, Håkan Widner, +4

Movement Disorders

Control of the activity of CAR-T cells within tumours via focused ultrasound

Yiqian Wu, Yahan Liu, Ziliang Huang, +12

Nature Biomedical Engineering

Medical UltrasoundFocused UltrasoundEngineeringCar-t CellsPower Ultrasound +6

Neuronal Properties, In Vivo Effects, and Pathology of a Huntington's Disease Patient-Derived Induced Pluripotent Stem Cells

Iksoo Jeon, Nayeon Lee, Jiayi Li, +17

Stem Cells

Ipsc LineCellular NeurobiologyRat ModelSocial SciencesNeuroregeneration +18

Deferoxamine inhibits iron induced hippocampal tau phosphorylation in the Alzheimer transgenic mouse brain

Chuang Guo, Pu Wang, Manli Zhong, +4

Neurochemistry International

Alzheimer's DiseaseDegenerative PathologyNeurochemical BiomarkersNeuroprotectionNeurology +6