Concepedia

Facile method to incorporate high-affinity ACAT/SOAT1 inhibitor F12511 into stealth liposome-based nanoparticle and demonstration of its efficacy in blocking cholesteryl ester biosynthesis without overt toxicity in neuronal cell culture

Adrianna L. De La Torre, C G Smith, Joseph E. Granger, Faith L. Anderson, Taylor C. Harned, Matthew C. Havrda, Catherine C.Y. Chang, Ta‐Yuan Chang

Journal of Neuroscience Methods · 2021 · 11 citations · 45 references

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45

‘Stealth’ corona-core nanoparticles surface modified by polyethylene glycol (PEG): influences of the corona (PEG chain length and surface density) and of the core composition on phagocytic uptake and plasma protein adsorption

Ruxandra Gref, Martín Luck, P. Quellec et al. · Colloids and Surfaces B Biointerfaces · 2000 · 1.7K citations

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Potentiating the antitumour response of CD8+ T cells by modulating cholesterol metabolism

Wei Yang, Yibing Bai, Ying Xiong et al. · Nature · 2016 · 1K citations · Full text

, , +15

Proteomics identifies new therapeutic targets of early-stage hepatocellular carcinoma

Ying Jiang, Aihua Sun, Yang Zhao et al. · Nature · 2019 · 980 citations

, , +14

Cholesteryl Ester Accumulation Induced by PTEN Loss and PI3K/AKT Activation Underlies Human Prostate Cancer Aggressiveness

Shuhua Yue, Junjie Li, Seung Young Lee et al. · Cell Metabolism · 2014 · 940 citations · Full text

, , +11

TREM2 Regulates Microglial Cholesterol Metabolism upon Chronic Phagocytic Challenge

Alicia Nugent, Karin Lin, Bettina van Lengerich et al. · Neuron · 2020 · 748 citations · Full text

, , +14