The protective effects of Omarigliptin against Lipopolysaccharide (LPS)- induced inflammatory response and expression of mucin 5AC (MUC5AC) in human bronchial epithelial cells

The AMP-activated protein kinase α2 catalytic subunit controls whole-body insulin sensitivity

Benoı̂t Viollet, Fabrizio Andréelli, Sebastian B. Jørgensen et al. · Journal of Clinical Investigation · 2003 · 488 citations

Life Sciences, Endocrinology, Physiology +16

Oxidative stress–induced mitochondrial dysfunction drives inflammation and airway smooth muscle remodeling in patients with chronic obstructive pulmonary disease

Coen Wiegman, Charalambos Michaeloudes, Gulammehdi Haji et al. · Journal of Allergy and Clinical Immunology · 2015 · 446 citations · Full text

Life Sciences, Cell Biology, Pathobiology +17

<scp>DPP</scp>‐4 Inhibitor Linagliptin Attenuates A<i>β</i>‐induced Cytotoxicity through Activation of <scp>AMPK</scp> in Neuronal Cells

Edy Kornelius, Chih‐Li Lin, Hsiu‐Han Chang et al. · CNS Neuroscience & Therapeutics · 2015 · 120 citations · Full text

Life Sciences, Neuroscience, Pharmacology +17

Oxidative stress induces GLUT4 translocation by activation of PI3‐K/Akt and dual AMPK kinase in cardiac myocytes

Takahiro Horie, Koh Ono, Kazuya Nagao et al. · Journal of Cellular Physiology · 2007 · 117 citations

Life Sciences, Cell Biology, Molecular Biology +13

A randomized, placebo-controlled study of the cardiovascular safety of the once-weekly DPP-4 inhibitor omarigliptin in patients with type 2 diabetes mellitus

Ira Gantz, Menghui Chen, Shailaja Suryawanshi et al. · Cardiovascular Diabetology · 2017 · 109 citations · Full text

Medicine, Pharmacology, Pharmacotherapy +14